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Neoplasm of lung

MedGen UID:
7400
•Concept ID:
C0024121
•
Neoplastic Process
Synonyms: Lung neoplasm; Neoplasm of the lung
SNOMED CT: Neoplasm of lung (126713003); Tumor of lung (126713003)
 
Related genes: PPP2R1B, PIK3CA, PRKN, SLC22A18, KRAS, IRF1, ERCC6, ERBB2, EGFR, CYP2A6, MAP3K8, CASP8, BRAF, FASLG
 
HPO: HP:0100526
Monarch Initiative: MONDO:0021117

Definition

Tumor of the lung. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Conditions with this feature

Small cell lung carcinoma
MedGen UID:
57450
•Concept ID:
C0149925
•
Neoplastic Process
Small cell lung cancer (SCLC) is a type of highly malignant lung cancer that is composed of small ovoid cells. In the past, SCLC was called oat cell carcinoma because the microscopic appearance of the cells was felt to resemble oats. SLCLC usually originates near the bronchi and in many cases may grow and metastasize quickly.
See: Condition Record
Small cell lung carcinoma

Professional guidelines

PubMed

Video assisted thoracoscopic surgery and lobectomy, sublobar resection, radiofrequency ablation, and stereotactic radiosurgery: advances and controversies in the management of early stage non-small cell lung cancer.
Pennathur A, Abbas G, Christie N, Landreneau R, Luketich JD
Curr Opin Pulm Med 2007 Jul;13(4):267-70. doi: 10.1097/MCP.0b013e3281c61a85. PMID: 17534171

Curated

NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology.
Febbo PG, Ladanyi M, Aldape KD, De Marzo AM, Hammond ME, Hayes DF, Iafrate AJ, Kelley RK, Marcucci G, Ogino S, Pao W, Sgroi DC, Birkeland ML
J Natl Compr Canc Netw 2011 Nov;9 Suppl 5:S1-32; quiz S33. doi: 10.6004/jnccn.2011.0137. PMID: 22138009

Suggested Reading

PubMed

National Working Group Meeting on ALK diagnostics in lung cancer.
Cooper W, Fox S, O'Toole S, Morey A, Frances G, Pavlakis N, O'Byrne K, Dettrick A, Leong T, Rathi V, Spagnolo D, Hemmings C, Singh M, Moffat D, Tsao MS, Wilner K, Buller R, Pitman Lowenthal S, Arifeen S, Binko J, Alam M
Asia Pac J Clin Oncol 2014 Apr;10 Suppl 2:11-7. doi: 10.1111/ajco.12190. PMID: 24673736

Recent clinical studies

Etiology

Diabetes, Metformin, and Lung Cancer: Retrospective Study of the Korean NHIS-HEALS Database.
Kim J, Hyun HJ, Choi EA, Yoo JW, Lee S, Jeong N, Shen JJ, You HS, Kim YS, Kang HT
Clin Lung Cancer 2020 Nov;21(6):e551-e559. Epub 2020 Apr 13 doi: 10.1016/j.cllc.2020.04.001. PMID: 32532664
Analysis of disease profile, and medical burden by lead exposure from hospital information systems in China.
Song H, Liu J, Cao Z, Luo W, Chen JY
BMC Public Health 2019 Aug 27;19(1):1170. doi: 10.1186/s12889-019-7515-5. PMID: 31455310Free PMC Article
An unusual case of peripartum pulmonary oedema.
Reddy YN, Sundaram V, Stamler JS
BMJ Case Rep 2013 Sep 26;2013 doi: 10.1136/bcr-2013-200150. PMID: 24072829Free PMC Article
Mortality among coal miners with pneumoconiosis in Poland.
Starzyński Z, Marek K, Kujawska A, Szymczak W
Int J Occup Med Environ Health 1996;9(4):279-89. PMID: 9117187

Diagnosis

Enlarging pulmonary cyst: a rare form of alveolar adenoma.
Sung YE, Moon MH
J Cardiothorac Surg 2023 Oct 31;18(1):303. doi: 10.1186/s13019-023-02409-9. PMID: 37907949Free PMC Article
Large mesenchymal cystic and chondroid pulmonary hamartoma mimicking lung cancer: Case report.
Ahn S, Lee H, Kang JK, Kim IS, Moon Y, Choi JS, Choi SY
J Cardiothorac Surg 2023 Oct 10;18(1):278. doi: 10.1186/s13019-023-02394-z. PMID: 37817244Free PMC Article
Intravitreal bevacizumab in treatment of iris metastasis from primary lung carcinoma.
Raval V, Saldanha M, Mittal R, Das T
BMJ Case Rep 2019 Sep 8;12(9) doi: 10.1136/bcr-2019-231097. PMID: 31501176Free PMC Article
An unusual case of peripartum pulmonary oedema.
Reddy YN, Sundaram V, Stamler JS
BMJ Case Rep 2013 Sep 26;2013 doi: 10.1136/bcr-2013-200150. PMID: 24072829Free PMC Article
Polymorphisms in the aurora-A gene is not associated with lung cancer in the Turkish population.
Dogan I, Ekmekci A, Yurdakul AS, Onen IH, Ozturk C, Cirak MY, Acar A, Konac E
DNA Cell Biol 2008 Aug;27(8):443-8. doi: 10.1089/dna.2007.0719. PMID: 18466087

Therapy

Diabetes, Metformin, and Lung Cancer: Retrospective Study of the Korean NHIS-HEALS Database.
Kim J, Hyun HJ, Choi EA, Yoo JW, Lee S, Jeong N, Shen JJ, You HS, Kim YS, Kang HT
Clin Lung Cancer 2020 Nov;21(6):e551-e559. Epub 2020 Apr 13 doi: 10.1016/j.cllc.2020.04.001. PMID: 32532664
Intravitreal bevacizumab in treatment of iris metastasis from primary lung carcinoma.
Raval V, Saldanha M, Mittal R, Das T
BMJ Case Rep 2019 Sep 8;12(9) doi: 10.1136/bcr-2019-231097. PMID: 31501176Free PMC Article
Analysis of disease profile, and medical burden by lead exposure from hospital information systems in China.
Song H, Liu J, Cao Z, Luo W, Chen JY
BMC Public Health 2019 Aug 27;19(1):1170. doi: 10.1186/s12889-019-7515-5. PMID: 31455310Free PMC Article
Mortality among coal miners with pneumoconiosis in Poland.
Starzyński Z, Marek K, Kujawska A, Szymczak W
Int J Occup Med Environ Health 1996;9(4):279-89. PMID: 9117187

Prognosis

Diabetes, Metformin, and Lung Cancer: Retrospective Study of the Korean NHIS-HEALS Database.
Kim J, Hyun HJ, Choi EA, Yoo JW, Lee S, Jeong N, Shen JJ, You HS, Kim YS, Kang HT
Clin Lung Cancer 2020 Nov;21(6):e551-e559. Epub 2020 Apr 13 doi: 10.1016/j.cllc.2020.04.001. PMID: 32532664
An unusual case of peripartum pulmonary oedema.
Reddy YN, Sundaram V, Stamler JS
BMJ Case Rep 2013 Sep 26;2013 doi: 10.1136/bcr-2013-200150. PMID: 24072829Free PMC Article
Mortality among coal miners with pneumoconiosis in Poland.
Starzyński Z, Marek K, Kujawska A, Szymczak W
Int J Occup Med Environ Health 1996;9(4):279-89. PMID: 9117187

Clinical prediction guides

Analysis of disease profile, and medical burden by lead exposure from hospital information systems in China.
Song H, Liu J, Cao Z, Luo W, Chen JY
BMC Public Health 2019 Aug 27;19(1):1170. doi: 10.1186/s12889-019-7515-5. PMID: 31455310Free PMC Article
An old woman with weight loss and chest pain.
Dursunoğlu N, Kiter G, Oztürk E, Tunç P, Colakoğlu N, Değirmencioğlu S, Yaren A
Tuberk Toraks 2010;58(1):85-8. PMID: 20517734

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2011
      NCCN Task Force report: Evaluating the clinical utility of tumor markers in oncology.

    Consumer resources

    Reviews

    Related information

    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

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